Sophie Postel-Vinay on new recommendations for phase 1 trials.
- June 2014
Hans Clevers on important research into stem cells in normal gut tissue.
- May 2014
Carolyn Taylor and Paul McGale find evidence to clarify guidelines for radiotherapy after mastectomy.
- April 2014
Richard Sullivan and Ajay Aggarwal on how physicians can tackle the issue of affordability in cancer care.
- March 2014
The 1st EORTC Cancer Survivorship Summit addressed the practical problems faced by cancer patients.
- February 2014
Charles Swanton on a study that maps genetic changes in cancers over time.
- January 2014
Presidents of various cancer societies make predictions for the coming year.
- December 2013
Precision diagnostics have great potential, but changes are needed to make them more available.
- November 2013
Highlights of the European Cancer Congress - cancer society presidents give their view.
- October 2013
Richard Schilsky on the changes needed as personalised medicine enters the clinic.
- September 2013
A new advance in immunotherapy is discussed by Jean-Charles Soria and Caroline Robert.
EJC News Focus – February 2013
The Hallmarks of Cancer – 12 years on
What does it take to write a paper that will be cited more than 12,000 times? In the case of Douglas Hanahan and Robert Weinberg, it was a day spent discussing the features common to all cancer cells. While the field of cancer cell biology was becoming dauntingly complex, they came up with a straightforward framework for understanding the cancer cell: it had, they said, six underlying essential features. The paper that brought these ideas together, The Hallmarks of Cancer, went on to become a publishing sensation.
More than 10 years on, they updated the paper and introduced another two potential hallmarks, but their basic idea has stood the test of time. Doug Hanahan (Swiss Institute for Experimental Cancer Research, Lausanne, Switzerland) gave the keynote lecture at ESMO 2012; Helen Saul caught up with him there.