- October 2015
Milena Sant on the latest results from the EUROCARE study.
- September 2015
The science behind the IARC code that could reduce cancer in Europe.
- July/August 2015
Thomas Helleday on an exciting new class of drug, MTH1 inhibitors.
- June 2015
Lesley Seymour and Jan Bogaerts on the future of RECIST.
- May 2015
Paul Workman on strategies for overcoming resistance to new drugs.
- April 2015
Highlights from the TAT Congress in Paris.
- March 2015
Christopher Wild on the exposome, a measure of environmental exposure.
- February 2015
Mathematicians are developing a blood flow model for metastasis.
- January 2015
René Bernards on discovering effective drug combinations.
- December 2014
Research on the high rate of burnout among young oncologists.
- November 2014
Carl June on the efficacy of CAR-T cells in treating leukaemia.
EJC News Focus – February 2013
The Hallmarks of Cancer – 12 years on
What does it take to write a paper that will be cited more than 12,000 times? In the case of Douglas Hanahan and Robert Weinberg, it was a day spent discussing the features common to all cancer cells. While the field of cancer cell biology was becoming dauntingly complex, they came up with a straightforward framework for understanding the cancer cell: it had, they said, six underlying essential features. The paper that brought these ideas together, The Hallmarks of Cancer, went on to become a publishing sensation.
More than 10 years on, they updated the paper and introduced another two potential hallmarks, but their basic idea has stood the test of time. Doug Hanahan (Swiss Institute for Experimental Cancer Research, Lausanne, Switzerland) gave the keynote lecture at ESMO 2012; Helen Saul caught up with him there.