- July/August 2015
Thomas Helleday on an exciting new class of drug, MTH1 inhibitors.
- June 2015
Lesley Seymour and Jan Bogaerts on the future of RECIST.
- May 2015
Paul Workman on strategies for overcoming resistance to new drugs.
- April 2015
Highlights from the TAT Congress in Paris.
- March 2015
Christopher Wild on the exposome, a measure of environmental exposure.
- February 2015
Mathematicians are developing a blood flow model for metastasis.
- January 2015
René Bernards on discovering effective drug combinations.
- December 2014
Research on the high rate of burnout among young oncologists.
- November 2014
Carl June on the efficacy of CAR-T cells in treating leukaemia.
- October 2014
News from ESMO 2014 with Solange Peters and Alexander Eggermont.
- September 2014
Discussing how healthcare systems can meet the needs of cancer survivors.
EJC News Focus – September 2013
EJC's Drug of the Year, 2013
Immunotherapy is finally emerged from the shadows as a realistic – and perhaps essential – tool in cancer control. After decades of painstaking research which yielded little benefit for patients, immunotherapy has entered a fresh phase with the development of new agents that can either activate the immune system or re-awaken silenced immune responses to a tumour.
The emerging paradigm, by which only the most effective immune cells are selectively harnessed to target the tumour, is an immediate advance for patients. It also holds the promise of future steps forward, as clinicians and researchers learn how best to use the new agents in combination.
In this month's EJC News Focus, Jean-Charles Soria and Caroline Robert, both from Institut Gustave Roussy, Paris-Sud, France, explain to Helen Saul why the Programmed Death-1 receptor (PD-1), and its ligand (PD-L1), have been recognised in EJC's Drug of the Year article, 2013.