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EJC News Focus – October 2014

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Precision Medicine at ESMO 2014

Advances in melanoma, advanced breast cancer and non-small cell lung cancer (NSCLC) provided a showcase for precision medicine at the ESMO Congress (Madrid; 26-30 September, 2014). New drugs which inhibit BRAF and MEK receptors may be more potent than existing agents in melanoma, while the CLEOPATRA study found that the addition of pertuzumab to standard trastuzumab/chemotherapy in metastatic HER2 positive breast cancer prolonged overall survival by 15 months. The results from IMPRESS were negative, but nevertheless provide valuable information for clinicians treating patients with NSCLC.

Research into precision medicine will require large scale cancer programmes. Cancer Core Europe is a new collaboration between six top European cancer centres: Institut Gustave Roussy (Paris), Cambridge Cancer Centre, Karolinska Institutet (Stockholm), Netherlands Cancer Institute (Amsterdam), VHIO (Barcelona) and the German Cancer Research Center, DFFZ (Heidelberg).

In this month's EJC News Focus, Solange Peters (Lausanne University Hospital, Switzerland) outlines the highlights of ESMO 2014 to Helen Saul, while Alexander Eggermont (IGR) explains how Cancer Core Europe will provide a framework for future European research.