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2016 editions

  • December 2016
    Joao Incio on mechanisms to explain why obesity promotes cancer.
  • November 2016
    Mike Stratton on how mutational changes in a cancer genome can point to the cause of the cancer.
  • October 2016
    Ruth Muschel on a new target for treatments for colorectal cancer.
  • September 2016
    Freddie Hamdy on the effectiveness of treatments for prostate cancer.
  • August 2016
    Moshe Oren discusses the effects of the microenvironment on cancer cells.
  • July 2016
    Richard Gilbertson on the 'bad luck hypothesis' for the cause of cancer.
  • June 2016
    Key advances in clinical trials.
  • May 2016
    Mark Lemmon on the underlying biochemistry of cancer.
  • April 2016
    Roger Stupp on using alternating electric fields as treatment.
  • March 2016
    Charlotte Vrinten on public perception of deaths from cancer.
  • February 2016
    Guillermo Garcia-Manero on myelodysplastic syndromes (MDS).
  • December 2015/January 2016
    Nazneen Rahman on germline genetic screening in ovarian cancer.

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EJC News Focus – March 2015

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The exposome: 'an idea whose time has come'

Given the task of measuring all environmental exposures that contribute to an individual's risk of disease – lifestyle, chemical, biological; all changing over time – you might think that it's just too difficult. On the other hand, you could see it as absolutely key to preventing cancer.

Those were the polarised views that greeted Christopher Wild's proposed 'exposome' ten years ago. The concept was inspired by progress in understanding the human genome, and is intended to complement it. Now, with the development of relevant technology in biomarkers, smartphones, and so on, enthusiasm for the idea among the global scientific community is taking off.

Here, Christopher Wild, now Director of International Agency for Research on Cancer, Lyon, France, explains more to Helen Saul

(Christopher Wild's original article is here.)