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  • December 2016
    Joao Incio on mechanisms to explain why obesity promotes cancer.
  • November 2016
    Mike Stratton on how mutational changes in a cancer genome can point to the cause of the cancer.
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    Ruth Muschel on a new target for treatments for colorectal cancer.
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    Freddie Hamdy on the effectiveness of treatments for prostate cancer.
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    Moshe Oren discusses the effects of the microenvironment on cancer cells.
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    Richard Gilbertson on the 'bad luck hypothesis' for the cause of cancer.
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    Key advances in clinical trials.
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    Mark Lemmon on the underlying biochemistry of cancer.
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    Roger Stupp on using alternating electric fields as treatment.
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    Charlotte Vrinten on public perception of deaths from cancer.
  • February 2016
    Guillermo Garcia-Manero on myelodysplastic syndromes (MDS).
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    Nazneen Rahman on germline genetic screening in ovarian cancer.

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EJC News Focus – April 2015

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Highlights from the TAT Congress (Paris, 2-4 March 2015)

Immunotherapy took centre stage at the 13th International Symposium on Targeted Anticancer Therapies (TAT 2015). The clinical success of these new agents in a range of tumour types is generating real excitement – but basic research has yet to answer some key questions. What is the mechanism of action of these agents, how are they best combined, would they work better with entirely new systems of drug administration?

Other presentations at TAT focused on CDK inhibitors; new data suggested new targets in solid tumours. And research in epigenetic modulation is revealing the potential of the second generation of agents, which have overcome earlier problems.

Here, Congress President Jean-Charles Soria, Lillian Siu (Princess Margaret Cancer Centre, Toronto) and Aurélien Marabelle (Institut Gustave Roussy, Paris) discuss the key themes of TAT with Helen Saul.