> Back to EJC

2016 editions

  • December 2016
    Joao Incio on mechanisms to explain why obesity promotes cancer.
  • November 2016
    Mike Stratton on how mutational changes in a cancer genome can point to the cause of the cancer.
  • October 2016
    Ruth Muschel on a new target for treatments for colorectal cancer.
  • September 2016
    Freddie Hamdy on the effectiveness of treatments for prostate cancer.
  • August 2016
    Moshe Oren discusses the effects of the microenvironment on cancer cells.
  • July 2016
    Richard Gilbertson on the 'bad luck hypothesis' for the cause of cancer.
  • June 2016
    Key advances in clinical trials.
  • May 2016
    Mark Lemmon on the underlying biochemistry of cancer.
  • April 2016
    Roger Stupp on using alternating electric fields as treatment.
  • March 2016
    Charlotte Vrinten on public perception of deaths from cancer.
  • February 2016
    Guillermo Garcia-Manero on myelodysplastic syndromes (MDS).
  • December 2015/January 2016
    Nazneen Rahman on germline genetic screening in ovarian cancer.

> All 2015 Editions

> All 2014 Editions

> All 2013 Editions

> All 2012 Editions

> All 2011 Editions

EJC News Focus – December 2015/January 2016

Loading EJC News Focus video

Missed opportunities to prevent ovarian cancer

The role of BRCA genes in breast and ovarian cancer was established 20 years ago and yet the numbers of BRCA-positive patients with ovarian cancer has remained stable. It means that, in the UK at least, opportunities for prevention of ovarian cancer are being missed.

In a keynote lecture at the European Cancer Congress in Vienna (25–29 September 2015), Nazneen Rahman (Institute of Cancer Research, London, UK) called for germline genetic screening to become part of routine care in ovarian cancer.

Intricate ethical and practical considerations, necessary for genetic screening in healthy populations, often do not apply in cancer patients. In this EJC News Focus, she tells Helen Saul that laborious procedures could be abandoned to make germline genetic screening, and the potential for prevention, much more widely available.